Polyphenolics and triterpenes presence in chloroform extract of Dicranopteris linearis leaves attenuated paracetamol-induced liver intoxication in rat
نویسندگان
چکیده
منابع مشابه
Effect of aqueous extract of Dicranopteris linearis leaves against paracetamol and carbon tetrachloride-induced liver toxicity in rats.
The present study aimed to determine the hepatoprotective activity of Dicranopteris linearis L. (family Gleicheniaceae) leaf aqueous extract (DLAE) using two models of liver injury in rats. Rats were divided into ten groups (n=6) and received dH2O (negative control), 200 mg/kg silymarin (positive control) or DLAE (50, 250 and 500 mg/kg) orally once daily for 7 consecutive days and on the 8th da...
متن کاملMethanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system
BACKGROUND The present study investigated the potential of methanolic extract of Dicranopteris linearis (MEDL) leaves to attenuate liver intoxication induced by acetaminophen (APAP) in rats. METHODS A group of mice (n = 5) treated orally with a single dose (5000 mg/kg) of MEDL was first subjected to the acute toxicity study using the OECD 420 model. In the hepatoprotective study, six groups o...
متن کاملEffect of methanol extract of Dicranopteris linearis against carbon tetrachloride- induced acute liver injury in rats
BACKGROUND Dicranopteris linearis (family Gleicheniaceae) has been reported to possess anti-inflammatory and antioxidant activities but no attempt has been made to study its hepatoprotective potential. The aim of the present study was to determine the hepatoprotective effect of methanol extracts of D. linearis (MEDL) against carbon tetrachloride (CCl4)-induced acute liver injury in rats. METH...
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15 صفحه اولattenuated lead induced apoptosis in rat hepatocytes in the presence of lycopersicon esculentum
lead (pb), has, for decades, being known for its adverse effects on various body organs and systems. in the present study, the damage of pb on the liver tissue apoptosis was investigated, and lycopersicon esculentum as an antioxidants source was administered orally to prevent the adverse effects of pb. eighteen wistar rats, randomized into three groups (n=6), were used for this study. animals i...
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ژورنال
عنوان ژورنال: BMC Complementary Medicine and Therapies
سال: 2021
ISSN: 2662-7671
DOI: 10.1186/s12906-020-03200-2